In short
Radiation therapy for pancreatic cancer uses high-energy rays to kill cancer cells [2]. It is often given with chemotherapy (chemoradiation) rather than alone [3]. Its use depends on the stage of the cancer and whether surgery was done [2].
The details
Radiation therapy is a treatment that targets specific areas of the body with radiation [2].
For patients who have had surgery but did not have all the tumor removed (incompletely resected tumors), chemoradiation may help them live longer [3]. This needs more study to confirm [2].
For patients whose cancer is "borderline resectable" (hard to remove with surgery), giving radiation before surgery is a promising option [2].
For patients with locally advanced cancer (cancer that has spread to nearby areas but not far away), there is no single standard treatment [3]. Giving chemotherapy first, then chemoradiation if the cancer does not grow, can lower the chance of the cancer coming back in that area [2].
Doctors try to reduce the size of the radiation field to help patients tolerate the treatment better [3]. They also account for tumor movement caused by breathing [2].
A technique called intensity modulated radiation therapy helps lower radiation doses to healthy organs nearby [3]. However, this technique is widely used but does not have strong evidence-based recommendations yet [2].
What to know
The use of radiation therapy for pancreatic cancer is still a subject of discussion among doctors [3]. Many techniques are being studied, and some do not have strong proof of benefit yet [2]. You should talk to your care team about which setting (before surgery, after surgery, or locally advanced) applies to you and what the evidence says for your specific case.