About & Trust
How PanClear is curated, how evidence is ranked, and what this site is (and isn’t).
What PanClear is
PanClear (panclear.com) is an independent pancreatic-cancer knowledge hub. It answers common questions about treatments, surgery, genetic testing and clinical trials in plain language, with every answer drawn from published, peer-reviewed research and ranked by evidence quality. Content is refreshed on a weekly cycle as new literature is indexed.
It exists for two audiences: patients and caregivers (plain-language guides, “what this means for me” summaries) and clinicians (denser, citation-linked views, evidence digests and controversy maps).
How evidence is ranked
Every answer is built from sources ranked by study design. Higher tiers outweigh lower ones when conclusions conflict:
e.g. NCCN, ESMO, ASCO, AGITG — expert consensus built on the full evidence base. Most actionable for care decisions.
The strongest single-study evidence. Practice-changing trials (PRODIGE 24, MPACT, POLO…) anchor our treatment pages.
Structured pooling of many studies — powerful, but only as good as the trials included.
Real-world outcomes; useful where trials don’t exist, but prone to selection bias.
Early signals. Clearly labelled “still investigational” wherever they appear.
Wherever a claim appears on PanClear, its source is linked directly to PubMed or the publisher so you can read the primary paper yourself.
How weekly updates work
- Ingest — new pancreatic-cancer literature (PubMed, trial registries, major guidelines) is indexed automatically.
- Rank — each source is scored by evidence tier, journal weight and citation signal.
- Synthesise — answers are regenerated against the ranked corpus; nothing publishes automatically without review.
- Publish — the site is rebuilt from the updated evidence base. The freshness stamp above shows the newest indexed paper.
Changelog
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Clinical review
Guides and answers on PanClear are curated and reviewed by Prof. Anubhav Mittal, HPB & robotic surgeon, St Leonards, NSW, Australia.
Conflicts & funding
PanClear carries no advertising, no sponsored content, and no pharmaceutical or device-industry funding. No one pays to influence what appears here.