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neuroendocrine tumours

Patients & families

In short

Neuroendocrine tumors (NENs) are a rare group of cancers that can grow slowly or quickly [3]. They often start in the pancreas or other parts of the digestive tract [4]. Treatment depends on whether the tumor is localized or has spread, and it may include surgery or special radiation therapy [3].

The details

  • Neuroendocrine tumors are divided into well-differentiated types, which grow slowly, and poorly differentiated types, which grow fast [3].
  • Surgery is the main cure for tumors that have not spread to other parts of the body [3].
  • For advanced disease, doctors may use a treatment called peptide receptor radionuclide therapy (PRRT) [4]. This uses a radioactive drug to target the tumor cells.
  • A study in Japan showed that PRRT helped control the disease for about 21 months on average [4]. It also improved hormone-related symptoms in many patients [4].
  • Patients with tumors in the pancreas or hindgut (the lower part of the large intestine) responded well to this therapy [4].
  • Because these tumors are rare, doctors recommend keeping detailed records and using a team of specialists to plan care [3].
  • What to know

    The research on PRRT comes from a study in Japan, so results may vary for other groups of people [4]. Treatment choices must consider many factors, such as the tumor type and the patient's health [3]. Always talk to your medical team about what is best for your specific situation.

    โš•๏ธ This is for learning, not treatment decisions. Always talk with your oncology team โ€” they know your full situation. The information here comes from published research and is meant to help you have better conversations with your doctors.
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